VETILOZIN-50%

is an antibiotic from the macrolide group and effective against Gram-positive and some gram-negative bacteria including Streptococcus, Staphylococcus, Corynebacterium, Clostridium, Pasteurella, erysipelothrix, spirochetes, chlamydia, treponema hyodisenteriae and mycoplasma.

During intramuscular injection antibiotic is rapidly distributed throughout the body and reaches maximum concentration in tissue approximately 1 hour after administration. Therapeutic effect of this antibiotic in tissues retains for at least 20 hours. It is eliminated primarily with urine and with milk in lactating animals.

During oral administration this antibiotic is quickly absorbed by gastrointestinal tract and is penetrated through all organs and tissues of the body. The highest level of tylosin is achieved in lungs, liver, kidneys and mammary glands. After single dose of Vetilozin drug therapeutic concentration of this antibiotic is retained in the body within 15-18 hours.

Tylosin is eliminated mainly with bile and in smaller quantities by urine and milk.

The drug is prescribed with drinking water. During treatment pigs and poultry shall take water only with antibiotic. Before applying recommended dose of the drug is dissolved in small quantity of water, by adding it to the powder, and then diluted with water to the drinking quantity. Mixture of the powder with feed is permitted. Boiling of such mixture is not allowed.

In order to prevent respiratory mycoplasmosis and infectious sinusitis in birds Vetilozin 50% powder is prescribed based on 1 g per 1 liter of water to:

- Breeding poultry aged 1-5, 28-29, 56-57 and 140-141 days;
- Chickens of commercial egg breeds and broilers aged 1-3 and 28 days, turkeys aged 1-3 and 28-29 days.

The same drug dose is administered as treatment in chickens within 3 days and in turkeys for 5 days. During dysentery and gastroenterokolitis in pigs the drug is administered twice a day at single dose 0.5 g per 1 L of water (or 10 mg per 1 kg of animal weight) within 3-10 days.

As therapeutic and preventive aid during bronchopneumonia in calves the drug is prescribed individually with water or milk twice a day based on 10 mg per 1 kg of the animal body weight within 7-14 days.

Vetilozin 50% powder is used as preventive care and treatment against respiratory mycoplasmosis in chicken and sinus infectious in turkey. This drug is prescribed for pigs against dysentery, gastroenterokolitis with bacterial etiology and for calves as therapeutic and prophylactic product against bronchopneumonia caused by pathogens sensitive to tylosin.

In some cases skin erythema and itching can be observed in pigs that shall disappear after drug discontinuation.

CONTRAINDICATIONS: Do not use the drug in laying hens as well as simultaneously with penicillin, cephalosporin and lincomycin, since it can reduce anti-bacterial effect of tylosin and at individual increased sensitivity to tylosin in animals.

Slaughtering of calves for meat shall be allowed 14 days after the last drug administration, pigs and poultry 5 days after the last drug administration. Meat of animals during urgent slaughter before expiry of specified period shall be used to feed flesh eaters.

Eggs obtained from poultry during treatment shall not be used for food purposes