Oksitetratsiklin-200 is an injectable medical drug containingoxytetracycline antibiotic as active ingredient.

This drug is a clear, slightly viscous liquid from light brown to dark brown color without visible mechanical particles. 1 ml of the drug contains 200 mg of oxytetracycline.

The product is prepackaged in glass vials by 10, 20, 50, 50, 100, 200 and 250ml. The drug should be stored with caution (see List B ) in a dry, dark place within the temperature range from +4ºC to +20ºC Shelf life is 2 years under specified storage conditions.


Oxytetracycline is a bacteriostatic antibiotic. Oxytetracycline is represented in the drug as a complex with magnesium which stipulates its long lasting (prolonged)
effect. Oxytetracycline as a drug component inhibits synthesis of bacterial protein by blocking bind of amino acid-tRNA with 30S ribosome subunit.

Antibiotic spectrum covers most gram-positive and gramnegative bacteria, namely Streptococcus, Staphylococcus, Corynebacterium, Clostridium, Erysipelothrix, Pasteurella, Fusobakterium, Salmonella, Pseudomonade, Haemophilus, Actinobacterium, Shigella, Escherichia, chlamydia, rickettsia, spirochetes and mycoplasma.

During intramuscular injection antibiotic is rapidly reabsorbed from the injection point and reaches maximum concentration in the tissue approximately 30-50 minutes after injection. Therapeutic effect of this antibiotic in tissues retains for at least 20 hours. It is eliminated primarily with urine and with milk in lactating animals.

It penetrates into all animal organs and tissues overcoming placental barrier. It is eliminated primarily with urine, bile and with milk as well in lactating animals.

The drug is administered intramuscularly by single shot based on 1ml per 10 kg of animal weight. Desired drug dose should be injected in several body areas based on assumption that maximum amount of administered drug per injection point should not exceed 20 ml in cattle, 5-10 ml in pigs and 5 ml in sheep and goats.

Oksitetratsiklin-100 is used for the following diseases:

• In cattle (mature animals and calves): pneumonia, mastitis, pasteurellosis, pleurisy, diphtheria in calves, foot rot, keratoconjunctivitis, wound infections, anaplasmosis, and secondary bacterial infections at viral diseases.

• In pigs: pneumonia, atrophic rhinitis, pasteurellosis, pleurisy, mastitis, rose, Mastitis-Metritis-Agalactia Syndrome, purulent synovitis, umbilical sepsis, abscess, wound and obstetric infections and secondary bacterial infections at viral diseases.

• In sheep and goats: enzootic abortion, foot rot, Metritis, Mastitis, peritonitis, wound infections and pneumonia in goats.

After drug injection local allergic reaction may be developed in the form of erythema and itching, which usually disappear without medical intervention. With development of severe allergic reaction intravenous calcium injection (calcium chloride, calcii borglukonas) or use of antihistamines (diphenylhidramine) shall be recommended.

CONTRAINDICATIONS: Individual sensitivity to the drug components.
It is not recommended to use this drug in conjunction with corticosteroid and estrogens. Due to apparent reduction of antibacterial effect of oxytetracycline it is not used in conjunction with such antibiotics as penicillin and cephalosporin.
This drug is not administered in horses, dogs, cats and other animals with renal insufficiency, pregnant females and newborn animals.

Slaughtering of animals for meat shall be allowed 12 days after the last drug
administration. Meat of animals during urgent slaughter before expiry of specified period shall be used to feed flesh eaters or for production of meat and bone meal tankage. Milk shall not be used for food purposes within 7 days after the last drug administration, but after boiling such milk may be used for feeding animals.