Enrofloxacin is an active ingredient – antibacterial drug of the fluroquinilone group of medications.

Enrovit-O contains 100 mg enrofloxacin in 1 ml of the drug. The drug by its appearance is a clear liquid of light-yellow to yellow color.

The drug is available in glass or plastic vials by 100, 200, 250, 500 and 1000g. The drug should be stored with caution (see List B) within the temperature range from +5 ºC to +25 ºC, in a dry place protected from direct sunlight. Shelf life is 24 months under specified storage conditions.


Enrofloxacin affects DNA gyrase, which inhibits apple acid biosynthesis in microorganisms. Antibacterial effect of enrofloxacin has been detected against Gram-positive (Staphylococcus, Streptococcus, Corynebacterium, Clostridium and Listeria monocytogenes) and Gram-negative bacteria (E. coli, Salmonella, Klebsiella, Proteus, Yersinia, Haemophilus influenzae bacteria, Pasteurella,
actinobacillus, Pseudomonas, Bordetella, Brucella, Campylobacter) and mycoplasmas.

Enrofloxacin is well and quickly absorbed by gastrointestinal tract and penetrates into all tissues and organs of the body. Maximum concentration in blood is achieved 0.5-1 h after administration and retains for 4-6 hours and therapeutic concentration - for 24 hours.

The drug doesn’t undergo biotransformation in the body and is eliminated mainly unchanged with urine and bile.

The drug is administered orally mixed with water once a day.

In ruminants, pigs and rabbits a daily dose is based on 0,5-1ml of the drug per 10 kg (2,5 – 5 mg enrofloxacin per 1 kg). Treatment is 3-5 days, depending on the disease severity.

• In poultry - 10 ml of the drug is diluted with 20 liters of drinking water and is administered within 3 days. In case of salmonellosis the treatment lasts up to 5 days.

During treatment animals and poultry should drink water containing Enrovit-O. Prepare fresh medicated water daily based on consumption needs. Half dose is administered within 3-5 days for prevention treatment.

The drug is prescribed for prevention and treatment of the following diseases in farm animals and poultry:

• Ruminants: enteritis, respiratory infections, colibacillosis, pasteurellosis, salmonellosis, mycoplasmosis, clostridioz, dysentery, leptospirosis;

• Rabbits: pasteurellosis, enterotoxemia, enteritis, dysentery, respiratory infections, listeriosis, endometritis, runny nose, rodentioz etc.;

• Pigs: bacterial diseases of gastrointestinal tract (kolidiareya, koliseptitsemiya) and bacterial respiratory diseases;

• Poultry: chronic respiratory diseases, septicemia, chicken cholera and chicken typhoid, salmonella, staphilococcosis, streptococcosis, mycoplasmosis, vibriosis hepatitis, etc.;

No side effects shall be observed if the drug is administered in recommended

CONTRAINDICATIONS: Do not administer the drug to hens-layers. It is restricted to use the drug simultaneously with chloramphenicol, macrolide antibiotic, tetracycline and nonsteroidal antiflammatory drugs. It is not recommended to use this drug at individual hypersensitivity to fluroquinolon.

Slaughter for meat of cattle, sheep, rabbits and chickens shall be allowed no earlier than 7 days, pigs - 5 days, turkeys - 14 days after the last drug administration. Milk and eggs shall not be used for food purposes within 7 days. Meat of urgently slaughtered animals as well as milk shall be used for feeding purpose only.